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Your blood pressure is a measurement of the pressure in your arteries while your heart is beating (systolic) and between beats (diastolic). Both of these values are important for diagnosing and managing high blood pressure. Systolic vs. diastolic blood pressure: How do they differ? Diastole and systole refer to when the heart muscles relax and contract. The balance between diastolic and systolic pressure determines... Explore the difference between systolic and diastolic blood pressure, their normal ranges, measurement methods, effects of high readings. The cardiac cycle events can be split into diastole and systole. The diastole indicates ventricular filling, while the systole indicates ventricular ejection or contraction. Though with varying pressures, the systole and diastole occur in both the right and left heart.