Having a calming, assuaging, or relieving effect.... Click for English pronunciations, examples sentences, video. The meaning of SOOTHING is tending to soothe; also : having a sedative effect. How to use soothing in a sentence. soothing (adjective) soothe (verb) soothing / ˈ suːðɪŋ/ adjective Britannica Dictionary definition of SOOTHING [more soothing; most soothing] : producing feelings of comfort or relief Soothing means making you feel calm or making something less painful. Learn how to use this adjective with synonyms, antonyms, and translations.