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Typical uses of phenytoin medication & Side Effects Phenytoin is a widely recognized medication primarily used to manage certain neurological disorders. Its main function is to stabilize neuronal membranes and prevent seizure activity. The compound has been in use since the 1930s and continues to be a critical component in the therapeutic arsenal against epilepsy and other conditions. This article aims to explore the various applications of phenytoin, providing a comprehensive look at its ... Phenytoin is primarily used to control seizures in epilepsy, which is a disorder that causes seizures. It may also be prescribed for other conditions as determined by a doctor. Phenytoin works by stabilizing electrical activity in the brain, which helps prevent seizures. Phenytoin is used in the treatment of epilepsy, epilepsy/seizures, mania, migraine, trigeminal neuralgia and seizures. Phenytoin is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain. Phenytoin is an anticonvulsant drug used in the prophylaxis and control of various types of seizures.