Patau syndrome: Is a syndrome caused by a

Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13. The extra genetic material disrupts normal development, causing multiple and complex organ defects. Patau syndrome, also called trisomy 13, is the least common and most severe of the viable autosomal trisomies. Median survival is fewer than 3 days. First identified as a cytogenetic syndrome in 1960, Patau syndrome is caused by an extra copy of chromosome 13, a medium-length acrocentric chromosome. Cytogenetic analysis is a necessary step in the prenatal diagnosis of Patau syndrome. Referral to a geneticist or genetic counselor is important for appropriate counseling regarding recurrence ... Trisomy 13, or Patau syndrome, is a genetic disorder that affects the development of a baby. Learn about the symptoms, diagnosis, and treatment options. Trisomy 13 was first described as the cause of a distinct clinical syndrome in 1960 by Dr. Patau et al. The clinical syndrome was initially characterized as "cerebral defects, apparent anophthalmia, cleft palate, hare lip, simian creases, trigger thumbs, polydactyly, and capillary hemangiomata."