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Osteoarthritis is joint pain that comes with wear and tear. Understand the causes, symptoms, diagnosis, and treatments for osteoarthritis . Osteoarthritis symptoms can usually be managed, although the damage to joints can't be reversed. Staying active, maintaining a healthy weight and receiving certain treatments might slow progression of the disease and help improve pain and joint function. Osteoarthritis is the most common form of arthritis . Tissues in the joint break down over time. Learn the symptoms & causes & if you might be at risk. Osteoarthritis is a degenerative joint disease that affects more than 32.5 million adults in the US. It can cause pain, stiffness, inflammation and loss of mobility in any joint, especially hands, knees, hips, lower back and neck.