Octreotide: MECHANISM OF ACTION

MECHANISM OF ACTION: Octreotide acetate is a synthetic somatostatin analogue with similar pharmacologic effects to naturally occurring somatostatin, but with a prolonged duration of action. It inhibits pathologically increased secretion of growth hormone, thyroid stimulating hormone, and serotonin, insulin, glucagon, and other peptides produced within the gastro-entero-pancreatic endocrine system.1 Somatostatin is cell cycle phase-specific, mediating arrest at the G1-phase.2 Long acting ... Octreotide is an Octapeptide analogue belonging to Antidiarrheal. Octreotide is a peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide-secreting tumors. After a subcutaneous dose, octreotide is absorbed completely upon administration. After the administration of an oral delayed-release capsule, peak concentrations were found to be 33% lower than after subcutaneous administration. The Cmax was attained at 1.67 ... Octreo 100mcg Injection is used in the treatment of Acromegaly,Bleeding esophageal varices,Carcinoid tumours. View Octreo 100mcg Injection (vial of 1.0 Injection) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.com