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Metabolic syndrome is a group of conditions that increase the risk of heart disease, stroke and type 2 diabetes . These conditions include high blood pressure, high blood sugar, too much fat around the waist, and high cholesterol or triglyceride levels. Metabolic syndrome is a cluster of conditions that increase the risk of diabetes and cardiovascular disease. It is associated with obesity, insulin resistance, high blood pressure, high blood sugar, and low HDL cholesterol. Metabolic syndrome is a group of conditions that together raise your risk of coronary heart disease, diabetes, stroke, and other serious health problems. Metabolic syndrome is also called insulin resistance syndrome . You may have metabolic syndrome if you have three or more of the following conditions. Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. It is becoming increasingly common worldwide, largely due to changes in lifestyle, diet, and rising rates of obesity.