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Symptoms common to Hodgkin lymphoma and non-Hodgkin lymphoma can include: Painless swelling of one or more lymph nodes in your neck, armpits or groin that doesn’t go away within a few weeks. Persistent fatigue, when you feel very tired day after day even after getting enough sleep. Lymphoma is a cancer that starts in the white blood cells This article looks at the two main types: Hodgkin lymphoma and non-Hodgkin lymphoma, as well as diagnosis and treatment. Swollen lymph nodes, night sweats and fevers are symptoms of lymphoma. Learn more from MD Anderson, a top-ranked cancer center. Common symptoms of having lymphoma include swelling of lymph nodes in your neck, in your armpits or your groin. This is often but not always painless and often could be associated with fevers, or unexplained weight loss, or drenching night sweats, sometimes chills, persistent fatigue.