Isotroin 20 Capsule is a retinoid medicine for severe acne that reduces sebum production and kills bacteria. It may cause dry skin, rash, and liver problems. It is unsafe during pregnancy and breastfeeding. Isotretinoin is a medication used to treat severe acne. It must not be taken by pregnant women or those who may become pregnant. Learn about the risks, side effects, and requirements of the iPLEDGE program for isotretinoin . Find patient medical information for Isotretinoin on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Easily Find Medication At Affordable Prices. Prime Members Can Enjoy Unlimited Free Shipping, Early Access To Lightning Deals and More.