HTTrack is a free and open source web crawler you can use to download entire websites. By default, HTTrack arranges the downloaded site by the original site's relative link-structure. Once you download a website with HTTrack, you can browse it in your preferred web browser. Mutation in huntingtin leads to Huntington’s disease. In this issue of Neuron, Saudou and Humbert highlight wild-type huntingtin-regulated molecular and cellular mechanisms that could be dysfunctional in Huntington‘s disease and the impact on the specificity and severity of this disorder. The Htt gene, also known as the huntingtin gene, plays a crucial role in the regulation of various cellular processes. This gene encodes the huntingtin protein, which is involved in important functions such as vesicle trafficking, gene transcription, and protein degradation. Mutations in the Htt gene can lead to the development of Huntington’s disease, a debilitating neurodegenerative disorder. One of the key features of the Htt gene is its ability to undergo alternative splicing, which ... Overview Hereditary hemorrhagic telangiectasia (tuh-lan-jee-uk-TAY-zhuh) is a condition that's passed through families, called inherited. It causes atypical links between arteries and veins called arteriovenous malformations (AVMs). The most common sites AVMs affect are the skin, nose, digestive system, lungs, brain and liver.
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