A drug or course of medical treatment used to restore health: discovered a new cure for ulcers. b. Restoration of health; recovery from disease: the likelihood of cure . c. Something that corrects or relieves a harmful or disturbing situation: The cats proved to be a good cure for our mouse problem. 2. Cure definition: a means of healing or restoring to health; remedy.. See examples of CURE used in a sentence. A cure is a substance or procedure that resolves a medical condition. This may include a medication, a surgical operation, a lifestyle change, or even a philosophical shift that alleviates a person's suffering or achieves a state of healing. CURE definition: 1. to make someone with an illness healthy again: 2. to stop someone doing or wanting something…. Learn more.