Hirschsprung disease: (HSCR) is a rare congenital disorder

Hirschsprung disease (HSCR) is a rare congenital disorder characterized by absence of ganglion cells in the bowel, leading to constipation, abdominal distension and intestinal obstruction. This ... Hirschsprung (HIRSH-sproong) disease is a condition in which nerve cells are missing in a baby's large intestine, resulting in bowel blockage. These nerve cells help move contents through the colon. Without them, the contents can back up and cause problems with passing stool. Hirschsprung disease is ... Hirschsprung Disease , also known as congenital aganglionic megacolon, is a rare but serious condition that affects the large intestine (colon) of infants. It is characterized by the absence of nerve cells in certain parts of the colon, leading to problems with bowel movements Hirschsprung disease , a neurocristopathy, is the most common cause of neonatal colonic obstruction (15-20%). It is commonly characterized by a short segment of colonic aganglionosis affecting term neonates, especially boys. Rarely, it can present in patients >10 years, termed adult Hirschsprung disease .