The meaning of DILIGENCE is steady, earnest, and energetic effort : devoted and painstaking work and application to accomplish an undertaking : assiduity. How to use diligence in a sentence. Definition of diligence noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. Diligence is a crucial aspect of mastering the English language, especially for those who are learning it as a second language. But what does diligence mean, Diligence means earnest and persistent application to an undertaking, or attentive care and heedfulness. It can also refer to a large stagecoach in French. See synonyms, antonyms, and translations in various languages.