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Cyclophosphamide is a medication that interferes with DNA and RNA synthesis and is used to treat cancers and autoimmune diseases. It has many side effects, such as low white blood cell counts, hair loss, and increased risk of cancer and infertility. Cyclophosphamide is used to treat a variety of different cancers. It is also sometimes used to treat severe symptoms of some connective tissue diseases ... Cyclophosphamide is a nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.