COE commonly refers to Center of Excellence, which is a team or entity that provides leadership, best practices, research, support, and training for a focus area within an organization. CoE stands for Center of Excellence, a dedicated team or unit that serves as a central hub for knowledge, expertise, and best practices in a specific area. Learn how CoEs can improve performance, enhance knowledge sharing, reduce costs, foster innovation, and gain competitive advantage. A Center of Excellence ( CoE ) is a centralized team or organizational structure that provides leadership, best practices, research, support, and training in a specific area of focus. CoEs are designed to drive the adoption of new methodologies, improve skills, and ensure that the organization remains at the forefront of its industry. A Center of Excellence (CoE) is a specialized unit within an organization that focuses on a particular area of expertise. CoEs can be found in various fields, such as technology, data, business processes, security, and innovation.