Calamine is a topical lotion or cream made from zinc oxide and ferric oxide. It is used to treat mild skin conditions such as sunburn, insect bites, or poison ivy. Calamine lotion is an over-the-counter medication that relieves itching and discomfort caused by minor skin allergies, such as poison ivy, insect bites, and sunburn. Find patient medical information for Calamine (Caladryl, Calahist, and Others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Calaminol Lotion, containing calamine as one of its active ingredients, may offer topical relief for various skin irritations, including minor burns, rashes, and itchiness associated with skin conditions during pregnancy Calaminol Lotion has mild antiseptic and anti-pruritic (anti-itch) properties, providing a soothing effect on the skin