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Infórmate sobre por qué los proveedores de atención médica generalmente no recomiendan una prueba de CA 125 para la detección del cáncer de ovario. A CA 125 test isn't accurate enough to use for ovarian cancer screening in general because many conditions can increase the level of this protein. Conditions that can cause an increase in CA 125 include many that aren't cancerous, such as menstruation and uterine fibroids. Certain cancers may also cause an increased level of CA 125 , including ovarian, endometrial, peritoneal and fallopian tube cancers. Surgery to remove your uterus may affect your risk of ovarian cancer, depending on the type of procedure you had. If your cyst appears solid and you're at high risk of ovarian cancer, your provider might order a cancer antigen 125 ( CA 125 ) test or other blood tests. CA 125 levels can also be elevated in noncancerous conditions, such as endometriosis and pelvic inflammatory disease.