Define amalgamation . amalgamation synonyms, amalgamation pronunciation, amalgamation translation, English dictionary definition of amalgamation . n. 1. The act of amalgamating or the condition resulting from this act. 2. A consolidation or merger, as of several corporations. 3. The production of a... AMALGAMATION definition: 1. the process in which separate organizations unite to form a larger organization or group, or an…. Learn more. Amalgamation is one of the several terms that are technically related to corporate finance and accounting. Read on to know the definition, what Amalgamation is, and how it works in reality. Amalgamation represents a significant corporate restructuring mechanism where two or more companies combine to form a single entity.