Synovial Fluid Synovial fluid , present in very small quantities in normal synovial joints, has two functions: lubrication and nutrition.62,63 Synovial fluid is a combination of a filtrate of plasma that enters the joint space from the subsynovial capillaries and hyaluronic acid, which is secreted by the synoviocytes. Synovial fluid is the thick liquid that lubricates your joints and keeps them moving smoothly . It’s on all of your joints, including in your knees, shoulders, hips, hands, and feet. A synovial fluid analysis is performed when pain, inflammation, or swelling occurs in a joint, or when there’s an accumulation of fluid with an unknown cause. Learn about the anatomy, functions, and biomechanics of synovium and synovial fluid , the lubricant and nourishing components of synovial joints. Find out how synovium and synovial fluid are involved in various joint diseases and pathologies, and how physiotherapy can help.