What does POC abbreviation stand for? Explore the list of 548 best POC meaning forms based on popularity. Most common POC abbreviation full forms updated in September 2025. POC is an abbreviation that can have different meanings depending on the context. Learn what POC stands for in business, medicine, gaming, slang, and more. Proof of concept is sometimes also known as a proof of principle. Proof of concept is often a key part of the product development process. The proof of concept is the first point where an organization can check if an idea has a chance of succeeding. Looking for online definition of POC or what POC stands for? POC is listed in the World's most authoritative dictionary of abbreviations and acronyms