Learn about Peyronie’s disease , the causes, how it develops, the risk factors, diagnosis, and treatment options, and clinical trials. Peyronie's disease is where plaques (segments of flat scar tissue) form under the skin of the penis. These plaques can cause the penis to bend or become indented during erections. The plaques can often be felt through the skin and can be painful. How Does the Penis Normally Work? The main roles of the penis are to carry urine and sperm out of the body. There are 3 tubes inside the penis. One is called the urethra. It is hollow and carries urine from the bladder through the penis to the ... Peyronie’s Disease vs Normal Curvature Peyronie's disease is a condition that affects the penis, causing it to develop an abnormal curvature. While some curvature is normal, Peyronie's disease can result in a significant bend or pain that can affect a man's sexual health and quality of life. This article will help you understand the differences between Peyronie's disease and normal penile curvature, along with the symptoms, causes, and treatment options for Peyronie's disease . Peyronie’s disease is an acquired connective tissue disease of the tunica albuginea of the penis which usually presents with penile curvature/deformity and a palpable penile plaque. It is more common in Caucasian men over the fifth decade of life, ...