Nomenclature definition: a set or system of names or terms , as those used in a particular science or art, by an individual or community, etc.. See examples of NOMENCLATURE used in a sentence. Nomenclature is the system or set of names used in a specific branch of learning or activity, as in biology or chemistry. Learn more about its synonyms, word origin, and usage with examples from Collins English Dictionary. NOMENCLATURE meaning : 1. a system for naming things, especially in a particular area of science: 2. a system for naming …. Learn more. Meaning Nomenclature refers to the naming conventions used in various disciplines, such as science, art, or specialized fields, to clearly identify and categorize things.