Missouri is a constituent state of the U.S. It is bordered by Iowa to the north; Illinois, Kentucky, and Tennessee to the east; Arkansas to the south; and Oklahoma, Kansas, and Nebraska to the west. The state’s major cities are Kansas City in the west and St. Louis in the east. Its capital is Jefferson City. Ready to chase your curiosity? At the University of Missouri , we’ve maintained a nearly 200-year reputation for the Missouri Method, our signature approach to hands-on learning through research, internships and other experiential settings. We're not just shaping future leaders here. By bringing together the nation’s best students, world-class faculty and a unique infrastructure for innovation, we're building a brighter future for Missouri and beyond. So, get ready to embrace the ... Missouri is a major center of beer brewing and has some of the most permissive alcohol laws in the U.S. [10] It is home to Anheuser-Busch, the world's largest beer producer, and produces Missouri wine, especially in the Missouri Rhineland. Explore Missouri ' s state flag, diverse geography, rich history, key facts, and comprehensive education system, including the University of Missouri System.