Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Dobutamine is an Antihypertensive agent belonging to Adrenergic agonist / Inotropic agents. Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Inactivated when given orally. Dobutamine is hepatically metabolized, and it ... Dobutamine is used in the treatment of Heart Failure, Low blood pressure, Decreased blood pressure. View Dobutamine’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Dobutamine injection is a prescription drug in the drug class of catecholamines. Dobutamine is prescribed to assist with cardiac output in a person with a failing heart due to heart disease or cardiac surgery.