Learn about Amyloidosis , including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find resources and Amyloidosis is a heterogeneous disease that results from the deposition of toxic insoluble beta-sheet fibrillar protein aggregates in different tissues. Amyloidosis can be acquired or hereditary. The disease can be localized or systemic. Amyloid can accumulate in the liver, spleen, kidney, heart, ne … Amyloidosis Amyloidosis is a clinical disorder caused by extracellular and/or intracellular deposition of insoluble, abnormal amyloid fibrils that alter the normal function of tissues. [5] Only 10% of amyloidosis deposits consist of components such as glycosaminoglycans (GAGs), apolipoprotein E (apoE), and serum amyloid P-component (SAP), while nearly 90% of the deposits consist of amyloid fibrils that are formed by the aggregation of misfolded proteins. These proteins either arise from ... Learn about amyloidosis , a rare disorder that causes abnormal proteins to clump on organs and tissues. Find out the causes, symptoms, diagnosis and treatment options for different types of amyloidosis .
